Tissue
& Organ Function-on-a-Chip
Related
Articles:
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33
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Jongho
Park, Gihyun Lee, Je-Kyun Park, "Functional
assessment of a bioprinted immuno-mimetic Peyer’s patch recapitulating
gut-associated lymphoid tissue," Adv. Healthcare
Mater., 14 (1) 2402722 (2025).
Supporting
Info.: Word
(docx, 1.4 MB), Video
S1 (mp4, 7.7 MB)
The
first two authors contributed equally to this work.
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32
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Gihyun
Lee, Soo Jee Kim, Yejin Choi, Jongho Park, Je-Kyun Park, "Bioprinting
of a multi-composition array to mimic intra-tumor heterogeneity
of glioblastoma for drug evaluation," Microsyst.
Nanoeng., 10, 186 (2024). OPEN
ACCESS
Supporting
Info. (pdf, 457 KB)
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31
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GGihyun Lee, Soo Jee
Kim, Je-Kyun Park,
"Bioprinted multi-composition array mimicking tumor microenvironments to
evaluate drug efficacy with multivariable analysis," Adv. Healthcare
Mater., 13
(22), 2303716 (2024).
OPEN
ACCESS
Supporting
Info.: Word
(docx, 4.9 MB), Video
S1 (mp4, 3.3 MB), and Video
S2 (mp4, 663.4 KB)
Hot
Topic: Microfluidics
Hot
Topic: Tumors and Cancer
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30
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Hwisoo
Kim, Bumsoo Kim, Soo Jee Kim, Yejin Choi, Irene Hae-Rim Kim, Jieun Han, Young-Gyun
Park, Yong-Mahn Han, Je-Kyun Park, "Reconfigurable hanging drop microarray
platform for on-demand preparation and analysis of spheroid array," Adv.
Healthcare
Mater., 13
(22), 2400501 (2024).
OPEN
ACCESS
Supporting
Info.: Word
(docx, 11.9 MB), Video
S1 (mp4, 4.2 MB), Video
S2 (mp4, 7.9 MB,
Video
S3 (mp4, 817.7 KB),
Video
S4 (mp4, 1.2 MB), and
Video S5 (mp4, 2.2 MB)
Hot
Topic: Tumors and Cancer
Featured
on the Frontispiece in Advanced Healthcare Materials
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29
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Soo Jee Kim, Gihyun Lee, Je-Kyun Park, "Hybrid biofabrication of heterogeneous 3D constructs using low-viscosity bioinks," ACS Appl. Mater. Inter., 15
(35), 41247-41257 (2023).
Supporting
Info. (pdf,
Movie
S1, Movie
S2, and Movie
S3)
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28
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Gihyun Lee, Soo Jee
Kim, Je-Kyun Park, "Fabrication of a self-assembled and vascularized tumor
array via bioprinting on a microfluidic chip,"
Lab Chip, 23 (18), 4079-4091 (2023).
Supporting
Info. (pdf,
Video
S1)
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27
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Gihyun
Lee, Soo Jee Kim, Je-Kyun Park, "Bioprinting of heterogeneous and multilayered
cell-hydrogel constructs using continuous multi-material printing and aerosol-based
crosslinking," STAR Protocols, 3 (2), 101303
(2022).
OPEN
ACCESS
https://star-protocols.cell.com/protocols/1564
Supporting
Information:
Movie 1 (mp4, 39.8 MB), Movie
2 (mp4, 25.7 MB)
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26
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Soo Jee Kim,
Gihyun
Lee, Je-Kyun Park, "Direct microextrusion printing of a low viscosity
hydrogel on a supportive microstructured bioprinting substrate for the vasculogenesis of
endothelial cells," Adv.
Mater. Technol., 7
(8),
2101326 (2022).
Supporting
Info. (pdf, 940.9 KB), Supporting
Movie 1 (mp4, 3.8 MB), and Movie
2 (mp4, 9.1 MB)
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25
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Hyewon
Roh, Hwisoo
Kim, Je-Kyun Park, "Construction of a fibroblast-associated tumor spheroid
model based on a collagen drop array chip," Biosensors,
11 (12), 506 (2021).
OPEN
ACCESS
Supporting
Info. (pdf, 729 KB)
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24
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Minkyung
Cho, Je-Kyun Park, "Modular 3D in vitro artery-mimicking multichannel system for recapitulating
vascular stenosis and inflammation," Micromachines,
12 (12), 1528 (2021). OPEN
ACCESS
Supporting
Info. (pdf, 806 KB)
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23
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Gihyun
Lee, Soo Jee Kim, Honggu Chun, Je-Kyun Park, "Multilayered and heterogeneous hydrogel
construct printing system with crosslinking aerosol," Biofabrication,
13 (4), 045027 (2021). 
Supporting
Info.: Word (docx, 3.47 MB), Movie 1 (mp4,
1.08 MB)
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22
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Hwisoo
Kim, Hyewon
Roh, Haseong Kim, Je-Kyun Park, "Droplet contact-based spheroid transfer technique as
a multi-step assay tool for spheroid arrays," Lab
Chip,
21 (21), 4155-4165 (2021). 
Supporting
Info. (pdf, 547 KB), Movie 1 (mp4, 3064 KB), Movie 2 (mp4, 5376
KB), and Movie 3 (mp4, 540 KB)
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21
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Jaejung
Son, Hee-Hoon Kim, Jun-Hee Lee, Won-Il Jeong, Je-Kyun Park, "Assembly
and disassembly of the micropatterned collagen sheets containing cells for location-based
cellular function analysis," BioChip
J., 15 (1) 77-89 (2021).
Featured on the Cover
Article
Supporting
Info. (docx, 1804 KB)
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20
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Featured
on the Cover Article in BioChip Journal (Issue 1, 2021)
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19
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Haewon
Seo, Jaejung Son, Je-Kyun Park, "Controlled 3D co-culture of beta cells and
endothelial cells in a micropatterned collagen sheet for reproducible construction
of an improved pancreatic pseudo-tissue," APL Bioeng., 4
(4), 046103 (2020). OPEN
ACCESS
The first two authors
contributed equally to this work.
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18
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Minkyung
Cho, Je-Kyun Park, "Fabrication of a perfusable 3D in vitro artery-mimicking
multichannel system for artery disease models," ACS Biomater. Sci. Eng., 6
(9),
5326-5336 (2020). 
Supporting
Info. (pdf, 541 KB)
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17
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Juhwan Park, Hwisoo
Kim, Je-Kyun Park, "Microfluidic channel-integrated hanging drop array
chip operated by pushbuttons for spheroid culture and analysis," Analyst, 145
(21), 6974-6980 (2020). 
Supporting
Info. (pdf, 349 KB), Movie
1 (mp4, 273 KB)
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16
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Young Lee, Soo
Jee Kim, Je-Kyun Park,
"Chips-on-a-plate device for monitoring cellular migration in
a microchannel-based intestinal follicle-associated epithelium model," Biomicrofluidics, 13
(6), 064127 (2019). 
Supporting
Info. (docx, 273KB)
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15
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Young
Lee, Gihyun Lee,
Minkyung Cho,
Je-Kyun Park, "Design criteria and standardization of a microfluidic
cell culture system for investigating cellular migration,"
J. Micromech.
Microeng.,
29 (4), 043003 (2019).
Invited
Topical Review
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14
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Jaejung
Son, Min Seo Bang, Je-Kyun Park, "Hand-maneuverable collagen sheet with micropatterns
for 3D modular tissue engineering," ACS Biomater. Sci. Eng.,
5 (1), 339-345 (2019). 
Supporting
Info. (pdf, 828 KB)
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13
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Simple
devices enhance the embedment of spheroids into hydrogel arrays,
AIP Scilight -- by Mary
Alexandra Agner, Scilight 2018, 290005 (2018);
https://doi.org/10.1063/1.5047432
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12
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Hwisoo Kim, Chang Hyun Cho, Je-Kyun Park, "High-throughput
culture and embedment of spheroid array using droplet contact-based spheroid
transfer," Biomicrofluidics, 12 (4), 044109
(2018). 
Supporting
Info. (doc, 3 MB, video mp4,
572 KB)
Featured
Article (July 1, 2018)
Highlighted
in AIP Scilight (Simple devices enhance the embedment of spheroids into
hydrogel arrays --- by Mary Alexandra Agner)
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11
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Young Lee, Je-Kyun Park,
"Microfabricated cell culture system for the live cell
observation of the multilayered proliferation of
undifferentiated HT-29
cells," BioChip
J., 11
(4), 308-315 (2017).
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10
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Chae Yun Bae, Jaejung Son,
Hail Kim, Je-Kyun Park,
"Demonstration of interposed modular hydrogel sheet for multicellular
analysis in a microfluidic assembly platform," Sci. Rep., 7,
1289 (2017).
OPEN
ACCESS
Supporting
Info. (pdf, 1.91 MB)
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9
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Chang
Hyun Cho,
Seyong Kwon, Je-Kyun Park,
"Assembly
of hydrogel units for 3D microenvironment in a poly(dimethylsiloxane) channel," Micro Nano Syst. Lett., 5,
2 (2017). OPEN
ACCESS
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8
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Jaejung Son, Chae Yun Bae, Je-Kyun Park, "Construction
of modular hydrogel sheets for micropatterned macro-scaled 3D cellular architecture,"
J.
Vis. Exp., 107, e53475, doi:10.3791/53475 (2016). 
Materials
List (pdf, 53.4 KB)
video
clip (MP4, 36.9 MB)
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7
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Commentary
in Biotechnology Journal: Stackable micropatterned hydrogels for
analysis of thick tissues in vitro by Bobak Mosadegh
See
accompanying article by Son et al. DOI 10.1002/biot.201500384
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6
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Jaejung Son, Chae Yun Bae, Je-Kyun Park, "Freestanding
stacked mesh-like hydrogel sheets enable the creation of complex macroscale
cellular scaffolds," Biotechnol.
J., 11 (4), 585-591 (2016). 
Supporting
Info. (zip, 6661 KB)
Supporting
Info. (pdf, 492 KB), video
clip 1 (mp4, 1.18 MB), video
clip 2 (mp4, 3.99 MB)
See
accompanying commentary by Bobak
Mosadegh DOI 10.1002/biot.201500562
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5
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Chae Yun Bae, Moon-kyung
Min, Hail Kim, Je-Kyun Park, "Geometric effect of the hydrogel
grid structure on in vitro formation of homogeneous MIN6 cell clusters," Lab Chip, 14
(13),
2183-2190 (2014). 
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4
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Wonhye
Lee, Chae Yun Bae, Seyong Kwon, Jaejung Son, Jinho Kim, Yong Jeong, Seung-Schik Yoo, Je-Kyun Park, "Cellular
hydrogel biopaper for patterned 3D cell culture and modular tissue reconstruction,"
Adv. Healthcare Mater., 1 (5), 635-639 (2012). 
Supporting
Info. (pdf,
366 KB; Video
mp4, 305 KB)
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3
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Featured
on the Inside Front Cover, Tissue Reconstruction (Adv. Healthcare
Mater. 5/2012) (page 530)
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2
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Wonhye
Lee, Jaejung Son, Seung-Schik Yoo, Je-Kyun Park, "Facile and biocompatible
fabrication of chemically sol-gel transitional hydrogel free-standing microarchitectures," Biomacromolecules, 12 (1), 14-18
(2011).
Supporting
Info. (pdf, 828 KB)
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1
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Joon Seok Lee, Eujin Um, Je-Kyun Park, Chan Beum Park,
"Microfluidic
self-assembly of insulin monomers into amyloid fibrils on a
solid
surface," Langmuir, 24 (14), 7068-7071
(2008).
Supporting
Info. (pdf, 3.32 MB)
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