Research Highlights

Biomimetic Scaffold for Cell/Tissue Engineering

Related Articles:


Chae Yun Bae, Jaejung Son, Hail Kim, Je-Kyun Park, "Demonstration of interposed modular hydrogel sheet for multicellular analysis in a microfluidic assembly platform," Sci. Rep., 7, 1289 (2017).      OPEN ACCESS  
External link Supporting Info. (pdf, 1.91 MB)


Hyun Ji Gi, Dongsik Han, Je-Kyun Park, "Optoelectrofluidic printing system for fabricating hydrogel sheets with on-demand patterned cells and microparticles," Biofabrication, 9 (1), 015011 (2017).  
External link Supporting Info. (pdf, 320 KB), Video 1 (avi, 1.47 MB), Video 2 (avi, 2.06 MB)  


Jaejung Son, Chae Yun Bae, Je-Kyun Park, "Construction of modular hydrogel sheets for micropatterned macro-scaled 3D cellular architecture," J. Vis. Exp., 107, e53475, doi:10.3791/53475 (2016).  


Commentary in Biotechnology Journal: Stackable micropatterned hydrogels for analysis of thick tissues in vitro by Bobak Mosadegh

External link See accompanying article by Son et al. DOI 10.1002/biot.201500384


Jaejung Son, Chae Yun Bae, Je-Kyun Park, "Freestanding stacked mesh-like hydrogel sheets enable the creation of complex macroscale cellular scaffolds," Biotechnol. J., 11 (4), 585-591 (2016).    
External link Supporting Info. (zip, 6661 KB)  

External link See accompanying commentary by Bobak Mosadegh DOI 10.1002/biot.201500562 


Chae Yun Bae, Moon-kyung Min, Hail Kim, Je-Kyun Park, "Geometric effect of the hydrogel grid structure on in vitro formation of homogeneous MIN6 cell clusters," Lab Chip, 14 (13), 2183-2190 (2014).  


Wonhye Lee, Chae Yun Bae, Seyong Kwon, Jaejung Son, Jinho Kim, Yong Jeong, Seung-Schik Yoo, Je-Kyun Park, "Cellular hydrogel biopaper for patterned 3D cell culture and modular tissue reconstruction," Adv. Healthcare Mater.1 (5), 635-639 (2012).  
External link Supporting Info. (pdf, 366 KB; movie 1, 1315 KB)


Featured on the Inside Front Cover, Tissue Reconstruction (Adv. Healthcare Mater. 5/2012) (page 530)


Wonhye Lee, Jaejung Son, Seung-Schik Yoo, Je-Kyun Park, "Facile and biocompatible fabrication of chemically sol-gel transitional hydrogel free-standing microarchitectures," Biomacromolecules, 12 (1), 14-18 (2011).    
External link Supporting Info. (pdf, 828 KB)



Spotlight Article, "3D bio-printing of multi-layered cell-laden fluidic hydrogel scaffold" in Biotechnology and Bioengineering (2010, Volume 105, Issue 6)



Wonhye Lee, Vivian Lee, Samuel Polio, Phillip Keegan, Jong-Hwan Lee, Krisztina Fischer, Je-Kyun Park, Seung-Schik Yoo, "On-demand three-dimensional freeform fabrication of multi-layered hydrogel scaffold with fluidic channels," Biotechnol. Bioeng., 105 (6), 1178-1186 (2010).
External link Selected as a Spotlight Article - 3D bio-printing of multi-layered cell-laden fluidic hydrogel scaffold



Wonhye Lee, Jason Pinckney, Vivian Lee, Jong-Hwan Lee, Krisztina Fischer, Samuel Polio, Je-Kyun Park, Seung-Schik Yoo, "Three-dimensional bioprinting of rat embryonic neural cells," NeuroReport, 20 (8), 798-803 (2009).
External link Featured on the Front Cover Image


Featured on the Front Cover Image of NeuroReport (May 27, 2009, Vol 20, Issue 8): Co-culture of bio-printed rat embryonic neurons and astrocytes in collagen matrix



Wonhye Lee, Jason C. Debasitis, Vivian K. Lee, Jong-Hwan Lee, Krisztina Fischer, Karl Edminster, Je-Kyun Park, Seung-Schik Yoo, "Multi-layered culture of human skin fibroblasts and keratinocytes through three-dimensional freeform fabrication," Biomaterials, 30 (8), 1587-1595 (2009).



Joon Seok Lee, Eujin Um, Je-Kyun Park, Chan Beum Park, "Microfluidic self-assembly of insulin monomers into amyloid fibrils on a solid surface," Langmuir, 24 (14), 7068-7071 (2008).
External link Supporting Info. (pdf, 3.32 MB)