Research Highlights

Microfluidic Point-of-Care Testing (POCT) Devices

Related Articles:


Juhwan Park, Dong Hyun Han, Sang-Hyun Hwang, Je-Kyun Park, "Reciprocating flow-assisted nucleic acid purification using a finger-actuated microfluidic device," Lab Chip, 20 (18), 3346-3353 (2020).   
The first two authors contributed equally to this work.
External link Supporting Info. Movie 1 (MP4, 2535 KB), Movie 2 (MP4, 2829 KB) 


Chi Hyun Kim, Juhwan Park, Soo Jee Kim, Dae-Hyun Ko, Song Ha Lee, Seok Jae Lee, Je-Kyun Park, Moon-Keun Lee, "On-site extraction and purification of bacterial nucleic acids from blood samples using an unpowered microfluidic device," Sens. Actuators B Chem., 320, 128346 (2020).
The first two authors contributed equally to this work.
External link Supporting Info. (docx, 44 KB)  


Younggeun Jo, Juhwan Park, Je-Kyun Park, "Colorimetric detection of Escherichia coli O157:H7 with signal enhancement using size-based filtration on a finger-powered microfluidic device," Sensors, 20 (8) 2267 (2020).    OPEN ACCESS
The first two authors contributed equally to this work.


Inside Back Cover of Lab on a Chip (Issue 7, 2020): Critical review of user-friendly microfluidic devices towards practical sample preparation in point-of-care-testing, which can facilitate mixing of multiple reagents, effective reaction between biomolecules, separation of target particles, and compartmentalization for high-throughput or digital analysis.


Juhwan Park, Dong Hyun Han, Je-Kyun Park, "Towards practical sample preparation in point-of-care testing: user-friendly microfluidic devices," Lab Chip, 20 (7), 1191-1203 (2020).  
External link Critical Review 
External link Featured on the Inside Back Cover Article  


Juhwan Park, Je-Kyun Park, "Finger-actuated microfluidic display for smart blood typing," Anal. Chem., 91 (18), 11636-11642 (2019).  
External link
Supporting Info. (pdf, 1.32 MB), Movie (MP4, 2.12 MB) 


Juhwan Park, Je-Kyun Park, "Integrated microfluidic pumps and valves operated by finger actuation," Lab Chip, 19 (18), 2973-2977 (2019).  
External link
Supporting Info. (pdf, 291 KB), Movie (MP4, 6853 KB)


Seonhee Lee, Juhwan Park, Je-Kyun Park, "Foldable paper-based analytical device for the detection of an acetylcholinesterase inhibitor using an angle-based readout," Sens. Actuators B Chem., 273, 322-327 (2018).


Juhwan Park, Je-Kyun Park, "Finger-actuated microfluidic device for the blood-cross matching test," Lab Chip, 18 (8), 1215-1222 (2018).
External link Supporting Info. (pdf, 526 KB) 


Joong Ho Shin, Jisoo Hong, Hyeyun Go, Juhwan Park, Minsuk Kong, Sangryeol Ryu, Kwang-Pyo Kim, Eunjung Roh, Je-Kyun Park, "Multiplexed detection of foodborne pathogens from contaminated lettuces using a handheld multistep lateral flow assay device," J. Agric. Food Chem., 66 (1), 290-297 (2018).  The first two authors contributed equally to this work.
External link Supporting Info. (pdf, 194.55 KB)


Minsuk Kong, Joong Ho Shin, Sunggi Heu, Je-Kyun Park, Sangryeol Ryu, "Lateral flow assay-based bacterial detection using engineered cell wall binding domains of a phage endolysin," Biosens. Bioelectron.,  96, 173-177 (2017).  The first two authors contributed equally to this work.
External link
Supporting Info. (docx, 1.68 MB)


Juhwan Park, Je-Kyun Park, "Pressed region integrated 3D paper-based microfluidic device that enables vertical flow multistep assays for the detection of C-reactive protein based on programmed reagent loading," Sens. Actuators B Chem., 246, 1049-1055 (2017).
External link Supporting Info. (doc, 991 KB) 


Joong Ho Shin, Je-Kyun Park, "Functional packaging of lateral flow strip allows simple delivery of multiple reagents for multistep assays," Anal. Chem., 88 (21), 10374-10378 (2016).  
External link Supporting Info. (pdf, 1.85 MB)  


ACS News Service Weekly PressPac: Wed Apr 06 05:31:00 EDT 2016 Paper-based test could help prevent food poisoning


Juhwan Park, Joong Ho Shin, Je-Kyun Park, "Pressed paper-based dipstick for detection of foodborne pathogens with multistep reactions," Anal. Chem., 88 (7), 3781-3788 (2016).
External link Supporting Info. (pdf, 864 KB) 

External link Highlighted in the ACS News Service Weekly PressPac (2016. 4. 6)



Dae-Sik Lee, Byoung Gu Jeon, Chunhwa Ihm, Je-Kyun Park, Mun Yeon Jung, "A simple and smart telemedicine device for developing regions: a pocket-sized colorimetric reader," Lab Chip, 11 (1), 120-126 (2011).    
External link Supporting Info. (pdf, 331 KB) and Movie (wmv, 17.9 MB)
External link Lab on a Chip Blog: Medicine gets smart (2010. 11. 26)  
External link Selected for Vir. J. Bio. Phys. Res. (2010)/ Volume 20 / Issue 12 / INSTRUMENTATION DEVELOPMENT (2010. 12. 15)



Sungho Ko, Bumjun Kim, Seong-Sik Jo, Se Young Oh, Je-Kyun Park, "Electrochemical detection of cardiac troponin I using a microfluidic chip with the surface-functionalized poly(dimethylsiloxane) channel," Biosens. Bioelectron., 23 (1), 51-59 (2007).



Yoonhee Jang, Se Young Oh, Je-Kyun Park, "In situ electrochemical enzyme immunoassay on a microchip with surface-functionalized poly(dimethylsiloxane) channel," Enzyme Microb. Technol., 39 (5), 1122-1127 (2006).



Suhyeon Kim, Je-Kyun Park, "Development of a test strip reader for a lateral flow membrane-based immunochromatographic assay," Biotechnol. Bioprocess Eng., 9 (2), 127-131 (2004).


Kang Shin Lee, Tae-Han Kim, Min-Chol Shin, Won-Yong Lee, Je-Kyun Park, "Disposable liposome immunosensor for theophylline combining an immunochromatographic membrane and a thick-film electrode," Anal. Chim. Acta., 380 (1), 17-26 (1999).